KBAT or HOTS

Peperiksaan Pusat Amali Sains untuk subjek Physics, Chemistry, Biology dan Additional Science SPM 2015

Biology Workshop Paper 2 and Paper 3 (SM Sains Kubang Pasu)

Jaundice among newborns

Jaundice refers to the yellow colour of the skin and whites of the eyes caused by excess bilirubin in the blood. Bilirubin is produced by the normal breakdown of red blood cells.

Normally, bilirubin passes through the liver and is excreted as bile through the intestines. Jaundice occurs when bilirubin builds up faster than a newborn's liver can break it down and pass it from the body. Reasons for this include:

  Newborns make more bilirubin than adults do since they have more turnover of red blood cells. 

  A newborn baby's still-developing liver may not yet be able to remove adequate bilirubin from the blood. 

  Too large an amount of bilirubin is reabsorbed from the intestines before the baby gets rid of it in the stool. 

High levels of bilirubin — usually above 25 mg — can cause deafness, cerebral palsy, or other forms of brain damage in some babies. In less common cases, jaundice may indicate the presence of another condition, such as an infection or a thyroid problem. The American Academy of Pediatrics (AAP) recommends that all infants should be examined for jaundice within a few days of birth.

Types of Jaundice

The most common types of jaundice are:

Physiological (normal) jaundice: occurring in most newborns, this mild jaundice is due to the immaturity of the baby's liver, which leads to a slow processing of bilirubin. It generally appears at 2 to 4 days of age and disappears by 1 to 2 weeks of age.

Jaundice of prematurity: occurs frequently in premature babies since they are even less ready to excrete bilirubin effectively. Jaundice in premature babies needs to be treated at a lower bilirubin level than in full term babies in order to avoid complications.

Breastfeeding jaundice: jaundice can occur when a breastfeeding baby is not getting enough breast milk because of difficulty with breastfeeding or because the mother's milk isn’t in yet. This is not caused by a problem with the breast milk itself, but by the baby not getting enough to drink.

Breast milk jaundice: in 1% to 2% of breastfed babies, jaundice may be caused by substances produced in their mother's breast milk that can cause the bilirubin level to rise. These can prevent the excretion of bilirubin through the intestines. It starts after the first 3 to 5 days and slowly improves over 3 to 12 weeks.

Treatments

In mild or moderate levels of jaundice, by 1 to 2 weeks of age the baby will take care of the excess bilirubin on its own. For high levels of jaundice, phototherapy — treatment with a special light that helps rid the body of the bilirubin by altering it or making it easier for your baby's liver to get rid of it — may be used.

More frequent feedings of breast milk or supplementing with formula to help infants pass the bilirubin in their stools may also be recommended. In rare cases, a blood exchange may be required to give a baby fresh blood and remove the bilirubin.

If your baby develops jaundice that seems to be from breast milk, your doctor may ask you to temporarily stop breastfeeding. During this time, you can pump your breasts so you can keep producing breast milk and you can start nursing again once the condition has cleared.

If the amount of bilirubin is high, your baby may be readmitted to the hospital for treatment. Once the bilirubin level drops and the treatment is stopped, it is unlikely that treatment for jaundice will need to be restarted.

Blood group incompatibility (Rh or ABO problems): if a baby has a different blood type than the mother, the mother might produce antibodies that destroy the infant's red blood cells. This creates a sudden buildup of bilirubin in the baby's blood. Incompatibility jaundice can begin as early as the first day of life. Rh problems once caused the most severe form of jaundice, but now can be prevented with an injection of Rh immune globulin to the mother within 72 hours after delivery, which prevents her from forming antibodies that might endanger any subsequent babies.

Symptoms and Diagnosis

Jaundice usually appears around the second or third day of life. It begins at the head and progresses downward. A jaundiced baby's skin will usually appear yellow first on the face, followed by the chest and stomach, and finally, the legs. It can also cause the whites of an infant's eyes to appear yellow.

Since many babies are now released from the hospital at 1 or 2 days of life, it is best for the baby to be seen by a doctor within 1 to 2 days of leaving the hospital to check for jaundice. Parents should also keep an eye on their infants to detect jaundice.

If you notice your baby’s skin or eyes looking yellow you should contact your child's doctor to see if significant jaundice is present.

At the doctor's office, a small sample of your infant's blood can be tested to measure the bilirubin level. Some offices use a light meter to get an approximate measurement, and then if it is high, check a blood sample. The seriousness of the jaundice will vary based on how many hours old your child is and the presence of other medical conditions.

Biological Terms

One of the keys to being successful in biology is being able to understand the terminology. Difficult biology words and terms can be made easy to understand by becoming familiar with common prefixes and suffixes used in biology. These affixes, derived from Latin and Greek roots, form the basis for many difficult biology words.

Below is a list of a few biology words and terms that many biology students find difficult to understand. By breaking these words down into discrete units, even the most complex terms can be understood. 

1. Autotroph

This word can be separated as follows: Auto - troph.

Auto - means self, troph - means nourish. Autotrophs are organisms capable of self nourishment.

2. Cytokinesis

This word can be separated as follows: Cyto - kinesis.

Cyto - means cell, kinesis - means movement. Cytokinesis refers to the movement of the cytoplasm that produces distinct daughter cells during cell division.

3. Eukaryote

This word can be separated as follows: Eu - karyo - te.

Eu - means true, karyo - means nucleus. A eukaryote is an organism whose cells contain a "true" membrane bound nucleus.

4. Heterozygous

This word can be separated as follows: Hetero - zyg - ous.

Hetero - means different, zyg - means yolk or union, ous - means characterized by or full of. Heterozygous refers to a union characterized by the joining of two different alleles for a given trait.

5. Hydrophilic

This word can be separated as follows: Hydro - philic.

Hydro - refers to water, philic - means love. Hydrophilic means water-loving.

6. Oligosaccharide

This word can be separated as follows: Oligo - saccharide.

Oligo - means few or little, saccharide - means sugar. An oligosaccharide is a carbohydrate that contains a small number of component sugars.

7. Osteoblast

This word can be separated as follows: Osteo - blast.

Osteo - means bone, blast - means bud or germ (early form of an organism). An osteoblast is a cell from which bone is derived.

8. Tegmentum

This word can be separated as follows: Teg - ment - um.

Teg - means cover, ment - refers to mind or brain. The tegmentum is the bundle of fibers that cover the brain.

Pneumonoultramicroscopicsilicovolcanoconiosis

Yes, this is an actual word. What does it mean? Biology can be filled with words that sometimes seem incomprehensible. By "dissecting" these words into discrete units, even the most complex terms can be understood. To demonstrate this concept, let's begin by performing biology word dissections on the word above.

To perform our biology word dissection, we'll need to proceed carefully. First, we come to the prefix (pneu-), or (pneumo-) which means lung. Next, is ultra, meaning extreme, and microscopic, meaning small. Now we come to (silico-), which refers to silicon, and (volcano-) which refers to the mineral particles that make up a volcano. Then we have (coni-), a derivative of the Greek word konis meaning dust. Finally, we have the suffix (-osis) which means affected with. Now lets rebuild what we have dissected:

Considering the prefix (pneumo-) and the suffix (-osis), we can determine that the lungs are affected with something. But what? Breaking down the rest of the terms we get extremely small (ultramicroscopic) silicon (silico-) and volcanic (volcano-) dust (coni-) particles. Thus, pneumonoultramicroscopicsilicovolcanoconiosis is a disease of the lungs resulting from the inhalation of very fine silicate or quartz dust. That wasn't so difficult, now was it?

Now that we've honed our dissection skills, let's try some frequently used biology terms. For instance:

Arthritis

(Arth-) refers to joints and (-itis) means inflammation. Arthritis is the inflammation of a joint(s).

Erythrocyte

(Erythro-) means red and (-cyte) means cell. Erythrocytes are red blood cells.

Okay, let's move on to more difficult words. For instance:

Electroencephalogram

Dissecting, we have (electro-), pertaining to electricity, (encephal-) meaning brain, and (-gram) meaning record. Together we have an electric brain record or EEG. Thus, we have a record of brain wave activity using electrical contacts.

Schizophrenia

Individuals with this disorder suffer from delusions and hallucinations. (Schis-) means split and (phren-) means mind.

Thermoacidophiles

These are ancient bacteria that live in extremely hot and acidic environments. (Therm-) means heat, next you have (-acid), and finally (phil-) means love. Together we have heat and acid lovers.

Once you understand the commonly used prefixes and suffixes, obtuse words are a piece of cake! Now that you know how to apply the word dissection technique, I'm sure you'll be able to determine the meaning of the word thigmotropism (thigmo - tropism).